New & effective proton pump inhibitors(PPIs).

Esomeprazole 40 mg provides more elective acid control than twice standard dose Of Omeprazole.

A Maintenance dose esomeprazole 20 mg provided greatest acid control & maintained into gastric acid PH > 4 for a longer period of time than maintenance dose lansoprazole 15 mg. Rabeprazole 10mg & pantoprazole 20 mg in healthy subject